SARM stands for Selective Androgen Receptor Modulators. These are pharmaceutical drugs that are still under research. They resemble their predecessor, banned anabolic steroids in terms of the chemical structure and action. The steroids got banned from selling and use because of high side effects, and the SARMs are claimed to be distinctive as they cause no adverse effects. Their risk and health tendency have been diagnosed clinically and accredited to be safe.
Thus SARM is simply a fitness product that aims to replace banned anabolic steroids. It is under the process of getting approval from the FDA.
The working of SARM is quite like anabolic steroids; that is, they block the androgen receptors. They work only for muscle tissues but nowhere else, unlike prostates.
It has all the perks that its predecessor, anabolic steroids, offered, except the side effects. It benefits in:
There are many types of SARMs available in the market, including Ostarine, Testolone, Cardarine, Ibutamoren, Ligandrol, Andarine, Myostatin, Stenabolic, and many more.
Let’s explore all of these:
Ostarine (MK-2866) is known to imitate the functioning of androgen or anabolic hormone testosterone. Testosterone is a male sexual hormone that promotes body fat burning and rebuilding lean muscle mass. SARM Ostarine, also known as Enobosarm or GTx-024, does exactly the same; that’s why it is considered the first in the list of best SARMs. However, it is mainly for quick muscle building.
Ostarine was initially made for people with low endogenous testosterone levels. It is for both men and women.
Ostarine saves muscle mass and causes loss of fat, hence increasing the body’s energy levels. It makes one more fit for both aerobic and anaerobic training. In bodybuilders, it has enhanced bone density and defense against serious injuries.
It doesn’t cause any hormonal disorders, but several users have reported other symptoms like constipation, diarrhea, stomach pain, nausea, and vomiting.
Testolone or RAD-140 is considered the best SARM for bulking. Being still under clinical trials, it is one of the favorite products of bodybuilders. But, do you know this bulking SARM was made to fight off breast cancer and muscle loss.
Working Of Testolone
It resembles androgen-receptor cells of the organism. Its action is very selective and offers very less harm to the user’s health. Testolone rebuilds or reconstructs lean muscle mass, affecting other steroid hormone receptors. It prevents muscle loss or waste but does not influence body fat mass.
RAD-140 can really reduce the risk of breast cancer and prostate cancer. It also plays a vital role in enhancing bone density and hence prevents fractures. In addition, it enhances brain activity by resisting the destruction of brain cells and delaying its aging process.
Though being less riskier than testosterone replacement therapy or anabolic steroids, testolone is still not safe for consumption. A 49-year old user reported getting his liver damaged by consuming this SARM. Other than this, there are multiple other side effects that its consumers show, like insomnia, lethargy, nausea, sleep disorders, and other relevant ones.
The side effects usually depend upon the amount and dosage of the consumed drug. In fact, testolone’s function of enhancing brain activity tends to lead to brain damage too.
Cardarine, also known as Endurobol, is less of a SARM and more like an immunity booster. Scientifically known as GW501516, it is a Peroxisome Profilerator- Activated Receptor (PPAR).
It is known for increasing physical strength, energy, endurance, body fat burning, and managing body weight effectively. Cardarine offers a boost in athletic performance and body cutting too. Not being a SARM, this PPAR has a slightly different active mechanism and outputs.
Some reports have revealed it to be leading to several anti-inflammatory effects on the organism. Unlike other chemicals, it does not affect CNS, but still, it has the ability to stimulate or speed up the growth of cancerous tumor cells. It was noticed when the drug was under clinical trials and was tested on a rat.
This MK-677 has discovered its place illegally that too in the black market. Its unique structure secretes growth hormone and a growth factor, IGF-1 that promotes athletic performance and numerous other physical attributes.
Its functioning resembles the hormone ghrelin, also known as the hunger hormone. It imitates the ghrelin’s actions, that is, binding to one of the ghrelin receptors (GHSR) and then promotes the production of growth hormone (HGH). Thus clearly, it impacts the user’s appetite. Ibutamoren also controls the user’s mood, pleasure, brain memory capacity, cognitive functions, and biological rhythms.
It has almost nill effect on the body’s hormone levels, just like cortisol, a stress hormone.
Anybody can consume this SARM except people sensitive to insulin and diabetic ones.
It is a mild chemical and has very few side effects. However, it can cause a sudden increase in appetite, insomnia, lethargy, resistance to insulin secretion, joint pain, and even enhanced prolactin levels in the body.
It is also one of the best SARMs. It is also known as Anabolicum and VK5211. It is still an unapproved SARM found on the black market, and it functions to promote bone density. It also acts as an athletic enhancement supplement. Ligandrol is still under clinical tests.
Though the manufacturers claim their product fits every age and gender group of people, the women customers claim it to be the most suitable SARM for them. It is because it increases the bone density in women during the menopause phase.
It boosts the strengthening process of muscles and bones. As a result, ligandrol forms lean muscle mass and defends against severe injuries. It also enhances physical strength and sexual functioning.
Ligandrol LGD-4033 has high selectivity and targets only the muscles and bones. Being ineffective towards other tissues makes it bear the minimum possible side effects. It is considered one of the best SARMs because of its mild nature as it shows only usual side effects like upset stomach, nausea, and pain in the abdomen.
It is advised to consume it in the limit as overdose can make usual symptoms very hyped and fatal.
It is a selective-androgen receptor that is considered one of the best SARMs. Its main function is to fight against osteoporosis, muscle waste, and enhanced mass muscle improvement. Andarine favors fat burning and body shape cutting too.
S4 Andarine is very strong and active in nature. It resembles anabolic steroids like Anavar and Winstrol in its working. It minimizes the lipoprotein lipase enzyme, which accumulates body fat and weight gain. It saves lean muscle mass from losing at the time of the cutting phase. It doesn’t cause fluid retention and bloating. In addition, S4 Andarine helps in protein synthesis and strengthens bones, joints, ligaments, and muscles.
It tends to cause night vision problems.
Myostatin (YK-11) is a supplement that promotes muscle building and energy benefits. Its chemical structure is based on 5-α-dihydrotestosterone (DHT), which is a hormone an organism produces naturally.
Its chemical structure is the most powerful form of testosterone. It causes a massive impact on muscle mass, bone density, energy stimulation, and fat loss.
It has shown results of organism intoxication. These are very dangerous to consume and are considered unfit for human and animal consumption.
It is under research by a professor at Scripps Research Institute, Thomas Burris. Also known as Stenabolic (SR9009), it is yet not confirmed if suitable for humans or not.
The chemical androgenic and estrogenic structure of Stenabolic makes it precise for consumption by both men and women.
It works by activating REV-ERB, increasing the circadian rhythm of the body. Circadian rhythm affects the user’s sleep cycle, mood, energy production, and other biochemical functions of daily life.
Though fitness lovers consume SARMs, some of those mentioned above are among the favorites of weight lifters and bodybuilders, but these are still under clinical diagnosis. Of course, these are advanced versions and replacements of anabolic steroids, but still, there are many recent cases of their reported side effects. The sales and purchase of these best SARMs are illegal. In fact, their prolonged usage has proved to be fatal. Other products available in the market are legal and tested to use that function even better than SARMs.
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